Ka Hopena Palekana o ka Microecology ʻIli ma ka ʻIli

Ka Hopena Palekana oʻIli Microecologyma ka ʻili

Hoʻopuka nā kelepa sebaceous i nā lipids, kahi i hoʻopili ʻia e nā microorganism e hana i kahi ʻili lipid emulsified. Loaʻa i kēia mau ʻili lipid nā waikawa momona manuahi, i ʻike ʻia hoʻi he mau ʻili waikawa, hiki ke hoʻopau i nā mea alkaline i haumia ma ka ʻili a kāohi i nā bacteria haole (bacteria hele). , ulu nā fungi a me nā microorganism pathogenic ʻē aʻe, no laila ʻo ka hana mua o ka flora ʻili maʻamau he hopena pale koʻikoʻi.

ʻO nā invaginations o ka ʻili a me nā appendages, me nā kelepa hou (sweat glands), nā kelepa sebaceous, a me nā follicles lauoho, he flora kū hoʻokahi ko lākou. Hoʻopili nā kelepa sebaceous i nā follicles lauoho e hana i ka ʻāpana sebaceous follicular, kahi e hūnā ai i kahi mea lipid waiwai i kapa ʻia ʻo sebum. ʻO Sebum kahi kiʻi pale hydrophobic e pale a lubricant i ka ʻili a me ka lauoho a hana ma ke ʻano he pale antibacterial. He hypoxic iki nā kelepa sebaceous, e kākoʻo ana i ka ulu ʻana o nā bacteria anaerobic facultative e like meP. acnes, nona ka P. acnes lipase e hoʻohaʻahaʻa i ka sebum, hydrolyzes triglycerides i loko o ka sebum, a hoʻokuʻu i nā waikawa momona manuahi. Hiki i nā bacteria ke hoʻopili i kēia mau waikawa momona manuahi, e kōkua ana i ka wehewehe ʻana i ke kolone ʻana o nā kelepa sebaceous e P. acnes, a ʻo kēia mau waikawa momona manuahi e hāʻawi pū i ka acidity o ka ʻili o ka ʻili (pH o 5). Nui nā bacteria pathogenic maʻamau, e like me Staphylococcus aureus a me Streptococcus pyogenes, i kāohi ʻia i loko o kahi ʻano acidic a no laila he kūpono no ka ulu ʻana o ka coagulase-negative staphylococci a me nā bacteria coryneform. Eia nō naʻe, ʻo ka occlusion o ka ʻili e hopena i ka hoʻonui ʻana o ka pH e makemake ai i ka ulu ʻana o S. aureus a me S. pyogenes. No ka mea, ʻoi aku ka nui o ka sebum triglycerides i hana ʻia e ke kanaka ma mua o nā holoholona ʻē aʻe, ʻoi aku ka nui o ka P. acnes colonizes i ka ʻili kanaka.