ʻO ka hopena pale o ka ʻili Microecology ma ka ʻili

ʻO ka hopena palekana oʻIli Microecologyma ka ʻili

Hoʻokuʻu ʻia nā lipids e nā kelepa sebaceous, kahi i hoʻololi ʻia e nā microorganism e hana i kahi kiʻi lipid emulsified. Loaʻa i kēia mau kiʻiʻoniʻoni lipid nā ʻakika momona manuahi, ʻike ʻia hoʻi he kiʻiʻoniʻoni waikawa, hiki ke hoʻokaʻawale i nā mea alkaline i haumia i ka ʻili a keʻakeʻa i nā huakini haole (passing bacteria). , ke ulu nei nā fungi a me nā microorganism pathogenic ʻē aʻe, no laila, ʻo ka hana mua o ka pua ʻili maʻamau he hopena pale koʻikoʻi.

ʻO ka hoʻokomo ʻana i ka ʻili a me nā mea hoʻohui, e komo pū me nā ʻili hou (sweat glands), sebaceous glands, a me nā follicles lauoho, loaʻa i kā lākou mau pua ʻokoʻa. Hoʻopili nā kelepa sebaceous i nā follicles lauoho e hana i ka follicular sebaceous unit, kahi e huna ai i kahi waiwai lipid waiwai i kapa ʻia he sebum. ʻO Sebum kahi kiʻi pale hydrophobic e pale a lubricates i ka ʻili a me ka lauoho a hana ma ke ʻano he pale antibacterial. He ʻano hypoxic nā kelepa sebaceous, e kākoʻo ana i ka ulu ʻana o nā bacteria anaerobic facultative e like meP. acnes, aia ka P. acnes lipase e hoʻohaʻahaʻa i ka sebum, hydrolyzes triglycerides i loko o ka sebum, a hoʻokuʻu i nā ʻakika momona manuahi. Hiki i ka bacteria ke hoʻopili i kēia mau ʻakika momona manuahi, e kōkua ana i ka wehewehe ʻana i ka noho ʻana o nā ʻili sebaceous e P. acnes, a ʻo kēia mau mea momona manuahi pū kekahi i ka acidity o ka ʻili (pH o 5). Nui nā maʻi maʻi pathogenic maʻamau, e like me Staphylococcus aureus a me Streptococcus pyogenes, i pāpā ʻia i loko o kahi ʻakika a no laila ua maikaʻi no ka ulu ʻana o ka coagulase-negative staphylococci a me ka coryneform bacteria. Eia naʻe, ʻo ka hoʻopaʻa ʻana o ka ʻili ka hopena i ka piʻi ʻana o ka pH e makemake i ka ulu ʻana o S. aureus a me S. pyogenes. Ma muli o ka hana ʻana o ke kanaka i nā triglycerides sebum ma mua o nā holoholona ʻē aʻe, ʻoi aku ka nui o ka P. acnes i ka ʻili kanaka.