Ka hopena o Squalene ma ka ʻili

ʻO ke ʻano o ka oxidation squalene aia i loko o kona wā haʻahaʻa ionization hiki ke hāʻawi a loaʻa paha i nā electrons me ka ʻole o ka hōʻino ʻana i ke ʻano molekala o nā cell, a hiki i ka squalene ke hoʻopau i ka hopena kaulahao o nā hydroperoxides ma ke ala lipid peroxidation. Ua hōʻike ʻia nā haʻawina ua hoʻokumu nui ʻia ka peroxidation o ka sebum e ka oxygen singlet, a ʻoi aku ka nui o ka paʻa o ka oxygen singlet o ka squalene i loko o ka sebum kanaka ma mua o nā lipids ʻē aʻe i loko o ka ʻili kanaka. mau ka make ʻana. Eia nō naʻe, pono e hoʻomaopopo ʻia ʻoiai hiki i ka squalene ke ālai i ka lipid peroxidation, ʻo nā huahana o ka squalene, e like me nā waikawa momona unsaturated, he hopena hoʻonāukiuki hoʻi i ka ʻili.

Hiki i ka squalene peroxide ke pāʻani i kahi kuleana nui i ka pathogenesis o ka acne. I loko o nā hiʻohiʻona hoʻokolohua holoholona, ​​​​ua hoʻokumu ʻia he comedogenic kiʻekiʻe ka squalene monoperoxide, a piʻi mālie ka nui o ka squalene peroxide ma lalo o ka irradiation UV. No laila, ua manaʻo ʻia e pono i nā poʻe maʻi acne ke makaʻala i ka pale ʻana i ka lā, a hiki i nā sunscreens ke pale aku i ka squalene peroxidation ma nā ʻano physiological i hoʻokumu ʻia e nā kukuna ultraviolet.

Mea kālailai ʻilihiki ke hoʻohana ʻia e ʻike i ka hopena o ka kirīmi lā. Hōʻike ʻia ke kiʻi UV i ka uliuli ʻeleʻele inā hoʻopili ʻia ka sunscreen kemika; inā hoʻopili ʻia ka sunscreen kino, he ʻālohilohi ke kiʻi, e like me ke koena fluorescent.