Ka hopena o Squalene ma ka ʻili

Aia ke ʻano o ka oxidation squalene i kona manawa paepae ionization haʻahaʻa hiki ke hāʻawi a loaʻa i nā electrons me ka ʻole o ka hoʻopōʻino ʻana i ke ʻano molekala o nā pūnaewele, a hiki i ka squalene ke hoʻopau i ke kaulahao o nā hydroperoxide i ke ala lipid peroxidation. Ua hōʻike ʻia nā haʻawina ʻo ka peroxidation o ka sebum ma muli o ka oxygen singlet, a ʻo ka singlet oxygen quenching rate mau o ka squalene i loko o ka sebum kanaka ʻoi aku ka nui ma mua o nā lipids ʻē aʻe i ka ʻili kanaka. pau loa. Eia nō naʻe, pono e hoʻomaopopo ʻia ʻoiai hiki i ka squalene ke kāohi i ka lipid peroxidation, nā huahana o ka squalene, e like me ka unsaturated fatty acids, he hopena hoʻonāukiuki i ka ʻili.

Hiki i ka Squalene peroxide ke hana nui i ka pathogenesis o ka haki. I loko o nā ʻano hoʻokolohua holoholona, ​​ua hoʻokumu ʻia ʻo squalene monoperoxide he comedogenic nui, a piʻi mālie ka ʻike o ka squalene peroxide ma lalo o ka UV irradiation. No laila, manaʻo ʻia e hoʻolohe nā poʻe maʻi i ka lā, a hiki i nā pale lā ke pale i ka squalene peroxidation ma nā ʻano physiological i hana ʻia e nā kukuna ultraviolet.

Mea nānā ʻilihiki ke hoʻohana ʻia e ʻike i ka hopena o ka lā cream. Hōʻike ʻia ke kiʻi UV i ka uliuli ʻeleʻele inā hoʻohana ʻia ka pale lā; inā hoʻohana ʻia ka pale lā kino, hoʻohālikelike ke kiʻi, e like me ke koena fluorescent.