Nā loli hoʻonohonoho a me nā biochemical epidermal i ka ʻelemakule ʻili

ʻO ke ʻano o ka metabolism o ka epidermis, ʻo ia ka neʻe mālie ʻana o nā keratinocytes basal i luna me ka hoʻokaʻawale ʻana o nā cell, a make hope loa e hana i kahi stratum corneum non-nucleated, a laila hāʻule. Manaʻo nui ʻia me ka piʻi ʻana o ka makahiki, ua hewa ka papa basal a me ka papa spinous, ua pālahalaha ka hui ʻana o ka epidermis a me ka dermis, a ua emi ka mānoanoa o ka epidermis. Ma ke ʻano he pale waho loa o ke kino kanaka, pili pono ka epidermis me ke kaiapuni o waho a ua maʻalahi loa ka hoʻopilikia ʻia e nā kumu o waho like ʻole. ʻO ka ʻelemakule epidermal ka mea maʻalahi loa e hōʻike i ka mana o ka makahiki a me nā kumu o waho i ka ʻelemakule o ke kanaka.

I loko o ka epidermis o ka ʻili ʻelemakule, piʻi ka ʻokoʻa o ka nui, ke ʻano a me nā waiwai hoʻoluʻu o nā cell basal layer, e pālahalaha mālie ka hui ʻana o ka epidermis a me ka dermis, e pāpaʻu ana ke kui epidermal, a emi iho ka mānoanoa o ka epidermis. E emi ana ka mānoanoa o ka epidermal ma kahi o 6.4% i kēlā me kēia ʻumi makahiki, a emi koke aku i nā wahine. E emi ana ka mānoanoa o ka epidermal me ka ʻelemakule. ʻIke nui ʻia kēia loli ma nā wahi i hōʻike ʻia, me nā ʻili extensor o ka maka, ka ʻāʻī, nā lima, a me nā lima lima. Hoʻololi nā keratinocytes i ke ʻano o ka ʻili, e lilo ana i mea pōkole a momona, ʻoiai e lilo ana nā keratinocytes i mea nui ma muli o ka pōkole o ka epidermal turnover, e piʻi ana ka manawa hoʻohou o ka epidermis ʻelemakule, e emi ana ka hana proliferative o nā cell epidermal, a e lahilahi ana ka epidermis. lahilahi, e lilo ana ka ʻili i ka elasticity a me ka wrinkle.

Ma muli o kēia mau loli morphological, ʻaʻole paʻa ka hui ʻana o ka epidermis-dermis a palupalu i ka pōʻino o waho. Hoʻemi mālie ka helu o nā melanocytes ma hope o 30 mau makahiki, emi ka hiki ke hoʻonui, a emi ka hana enzymatic o nā melanocytes ma ka wikiwiki o 8%-20% i kēlā me kēia ʻumi makahiki. ʻOiai ʻaʻole maʻalahi ka ʻili e ʻeleʻele, ua maʻalahi nā melanocytes i ka hoʻonui kūloko e hana i nā kiko pigmentation, ʻoi aku hoʻi i nā wahi i hōʻike ʻia e ka lā. Hoʻemi ʻia hoʻi nā cell Langerhans, e hoʻemi ana i ka hana pale ʻili a hiki ke loaʻa i nā maʻi lele.

Mea hoʻopili ʻilihiki ke hoʻohana ʻia ka mīkini e ʻike i nā wrinkles ʻili maka, ke ʻano, ka nalowale o ka collagen, a me ke ʻano o ka maka e kōkua i ka ʻike ʻana i ka ʻelemakule o ka ʻili maka.