Epidermal structural and biochemical hoʻololi i ka ʻelemakule ʻili

ʻO ka metabolism o ka epidermis ʻo ia ka neʻe ʻana o nā keratinocytes basal i luna me ka hoʻokaʻawale ʻana o ke kelepona, a make i ka hana ʻana i kahi stratum corneum non-nucleated, a laila hāʻule. Manaʻo nui ʻia me ka piʻi ʻana o ka makahiki, pilikia ka papa basal a me ka ʻāpana spinous, palahalaha ka hui o ka epidermis a me ka dermis, a emi ka mānoanoa o ka epidermis. Ma ke ʻano he pale ʻoi loa o ke kino o ke kanaka, pili pololei ka epidermis me ke kaiapuni o waho a maʻalahi loa ka hopena e nā ʻano mea like ʻole. Hōʻike maʻalahi ka ʻelemakule epidermal i ka mana o ka makahiki a me nā kumu o waho i ka ʻelemakule kanaka.

I loko o ka epidermis o ka ʻili kahiko, hoʻonui ʻia ka loli o ka nui, morphology a me nā waiwai o ka ʻili o nā cell layer basal, e hele mālie ka hui ʻana o ka epidermis a me nā dermis, lilo ka pāpaʻu o ka epidermis, a emi ka mānoanoa o ka epidermis. Ke emi nei ka mānoanoa o ka Epidermal ma kahi o 6.4% i kēlā me kēia ʻumi makahiki, a ʻoi aku ka wikiwiki o ka emi ʻana o nā wahine. Ke emi nei ka mānoanoa Epidermal me ka makahiki. Hoʻolaha nui ʻia kēia hoʻololi ma nā wahi i hōʻike ʻia, me nā ʻaoʻao extensor o ka maka, ka ʻāʻī, nā lima, a me nā lima. Hoʻololi nā keratinocytes i ke ʻano o ka makahiki o ka ʻili, lilo a pōkole a momona, ʻoiai keratinocytes e nui aʻe ma muli o ka huli ʻana o ka epidermal pōkole, piʻi ka manawa hou o ka epidermis elemakule, emi ka hana proliferative o nā epidermis, a ʻoi aku ka lahilahi o ka epidermis. lahilahi, e lilo ai ka ʻili i ka elasticity a me ka wrinkle.

Ma muli o kēia mau hoʻololi morphological, ʻaʻole paʻa ka hui ʻana o ka epidermis-dermis a paʻakikī i ka pōʻino o waho. Ke emi malie nei ka heluna o na melanocytes ma hope o ke 30 o ka makahiki, emi ka mana proliferative, a emi iho ka hana enzymatic o na melanocytes ma kahi o 8%-20% no na makahiki he umi. ʻOiai ʻaʻole maʻalahi ka ʻili o ka ʻili, maʻalahi nā melanocytes i ka hoʻonui kūloko e hana i nā kiko pigmentation, ʻoi loa ma nā wahi i ʻike ʻia e ka lā. Hoʻemi pū ʻia nā pūnaewele Langerhans, e hoʻemi ana ka hana pale pale o ka ʻili a hiki i nā maʻi maʻi.

ʻili ʻiliHiki ke hoʻohana ʻia ka mīkini e ʻike i nā wrinkle o ka ʻili maka, ke ʻano, ka nalowale ʻana o ka collagen, a me ke ʻano o ka helehelena e kōkua i ka ʻike ʻana i ka ʻelemakule o ka ʻili.